Squamous cell carcinoma of the vulva in a patient with androgen insensitivity syndrome.

نویسندگان

  • H K Haefner
  • K Y Terada
  • G W Morley
  • K P Davis
چکیده

The complete form of androgen insensitivity syndrome (testicular feminization) occurs in a 46,XY karyotype with a mutant X-linked recessive gene that is responsible for the androgen intracellular receptor [l]. An individual with androgen insensitivity syndrome is a male pseudohermaphrodite. Phenotypic characterizations include scanty or absent axillary and pubic hair, slight vulvar hair, a rudimentary or absent vagina, euchnoidal structure, and breasts with small nipples and pale areolae. Cancers, in association with androgen insensitivity syndrome, have been thoroughly investigated. Neoplasms arising from the gonads and the neovagina have been reported. The following is the first report of squamous cell carcinoma of the vulva in a patient with androgen insensitivity syndrome.

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عنوان ژورنال:
  • Gynecologic oncology

دوره 38 1  شماره 

صفحات  -

تاریخ انتشار 1990